The Incidence of Epstein Barr Virus Antibodies in Hodgkins Lymphoma

Abstract

The association of Epstein Barr Virus (EBV) with Hodgkins lymphoma (HL) seems to depend on many factors such as geographical area , histological subtype and age. The present study included (30) patients having HL (18 males and 12 females) with age ranged 25 – 53 years, where histopathological sections reviewed. A second group regarded as control group complained of non malignant disorders (25)patients with age ranged (20 -55) years was identified that VCA –lgG and EAlgG were significantly higher (p 0.05) in HL group compared with control group. EBV positive is more prevalent in mixed cellularity subtype (56.6%) of all cases examined.The significant association between EBV and HL that was found further strengthens the suggestion that all cases of HL should be assessed for EBV status by immunohistochemistry because its presence may have a significant impact on prognosis and response to therapy.