Cytotoxicity and Cytogenetic Study of Crud Extract of juglans spp

Abstract

The aim of this study was cytotoxic and cytogenetic study of crude extract of juglans spp on Human Glioblastoma cell line (AMGM) and normal cell line (REF) before and after treatment on 24 and 48 hrs. of exposure time.
The results have showed a significant effect between concentrations started with 39.1 µg/ml compared with control after 72 hrs. of exposure time and with no significant effect on all concentrations compared with control on normal cell line (REF); whereas the results of mitotic index have showed a significant effect for the concentrations (312.5، 156.2، 78.1 و39.1 (µg/ml compared with control.