Immunology study for NDV treatment in mice Bearing mammary adenocarcinoma tumor

Authors

  • Ahmed M. Al-Shamery Iraqi Center for cancer and medical genetics research, Almustansiriya University.
  • Nahi Y. Yaseen Iraqi center for cancer and medical genetics research / Al Mustansiriya University
  • Mohammed J. Alwan College of veterinary medicine, Baghdad University

DOI:

https://doi.org/10.29409/ijcmg.v4i1.50

Abstract

Newcastle disease virus selectively kills human cancer cells versus normal cells.Newcastle disease virus has pleiotropic immune stimulatory properties. This study was conducted to investigate the ability of Iraqi strain of NDV to induce immune stimulation when used as oncolytic agent by intratumoral injection, IL-2 and IFN-gamm as well as CD8 and CD56 were used as parameters to determine of immune stimulation properties. The results showed high immune stimulatory effect for Iraqi strain of NDV.

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Published

2011-06-01

Issue

Vol. 4 No. 1 (2011)

Section

Cancer Research

License

Copyright (c) 2011 Iraqi Journal of Cancer and Medical Genetics

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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